One of the classical Turkish literary poets who lived in the 16th century is Handani. Handânî was born in 1539/40 and lived during the reign of Suleiman the Magnificent Selim II, and Murat III. There is no information about the poet's place of birth, his occupation other than being a poet, and the date of his death. According to the available data, his only known work is his Divan which consists of 49 eulogies, 15 masnavi, 44 musammat, 105 ghazals, 58 verses and 44 tuyug, and there are four identifiable copies of this diwan. The diwan, which deals mainly with religious Sufi themes, also mentions certain numbers in connection with number symbolism. The numbers in question are 2, 3, 4, 5, 7, 12, and 17 respectively, and the number four was tried to be evaluated in this study. The number four is considered an idealized number by the Pythagoreans, who shaped their belief system through numbers. The four, the representation of perfection, appears symbolically in both religious-Sufic literature and Turkish culture. In this sense, the poet treated the number four in two qasidas, one of 33 and one of 101 couplets. In the relevant poems, the importance of the number four is explained by giving examples of the four compositions (four seasons, four directions, four fards of wudu, four angels, four madhhabs, four caliphs, four fards of going on pilgrimage), and thus it is high-lighted that the number has a symbolic meaning. In the study, brief information about Handani's life is given and based on the two odes mentioned, the way in which the poet handles the number four is explained with sample couplets.